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This paper surveys the scientific literature investigating how estrogen and stress hormones have different effects on brain tissue and cognition. We propose that the dramatic decrease in estrogen experienced during menopause may make women more vulnerable to the negative effects of stress hormones on the brain and cognition. However, maintaining estrogen levels after menopause may combat those effects in women without contraindications for estrogen treatment.

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This page is a summary of: Actions and interactions of estradiol and glucocorticoids in cognition and the brain: Implications for aging women, Neuroscience & Biobehavioral Reviews, August 2015, Elsevier, DOI: 10.1016/j.neubiorev.2015.04.005.
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