What is it about?

We determined the efficacy of coenzyme Q10 supplementation on semen parameters, sperm function and reproductive hormone profiles in infertile men.

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Why is it important?

The distress and personal devastation experienced by couples with infertility has been documented since the beginning of recorded time in cultures throughout the world. The social and psychological consequences of involuntary childlessness in developing countries are more severe. Common scenarios include unstable marriages, divorce, polygamy and ostracism of the women.


This study indicates that oral supplementation with CoQ10 significantly improves semen parameters compared with that of placebo. Although this observation may not be clinically relevant, we propose that because of its antioxidant effects and safety profile, CoQ10 should be considered a good candidate for treatment in infertile men with idiopathic oligoasthenoteratospermia. A longer term study with different treatment regimens is needed to draw a final conclusion.

Dr Mohammad Reza Safarinejad
University of Medical Sceices

Read the Original

This page is a summary of: Efficacy of Coenzyme Q10 on Semen Parameters, Sperm Function and Reproductive Hormones in Infertile Men, The Journal of Urology, July 2009, Wolters Kluwer Health,
DOI: 10.1016/j.juro.2009.02.121.
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