What is it about?
This study tested whether individuals with at least 1 copy of the short (S) or long (L)(G) allele of the serotonin transporter gene-linked polymorphic region exhibit a greater incidence of premature ejaculation compared with L(A)L(A) individuals.
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Why is it important?
Premature ejaculation has been reported as the most common male sexual dysfunction with global prevalence rates estimated at approximately 30%. McMahon proposed psychogenic and biogenic causes of PE. The biological causes considered include penile hypersensitivity, a hyperexcitable ejaculatory reflex, increased sexual arousability, possible endocrinopathy, a genetic predisposition and central 5-hydroxytryptamine (5-HT or serotonin) receptor dysfunction.
Read the Original
This page is a summary of: Polymorphisms of the Serotonin Transporter Gene and Their Relation to Premature Ejaculation in Individuals from Iran, The Journal of Urology, June 2009, Wolters Kluwer Health,
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