Substitution of Glu122 by Glutamine Revealed the Function of the Second Water Molecule as a Proton Donor in the Binuclear Metal Enzyme Creatininase

  • Kinuyo Yamashita, Yoshitaka Nakajima, Hayato Matsushita, Yoshiaki Nishiya, Ryuji Yamazawa, Yu-fan Wu, Futoshi Matsubara, Hiroshi Oyama, Kiyoshi Ito, Tadashi Yoshimoto
  • Journal of Molecular Biology, March 2010, Elsevier
  • DOI: 10.1016/j.jmb.2009.12.045

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http://dx.doi.org/10.1016/j.jmb.2009.12.045