Binding of a Noncovalent Inhibitor Exploiting the S′ region Stabilizes the Hepatitis C virus NS3 Protease Conformation in the Absence of Cofactor

Mariana Gallo, Matteo Pennestri, Matthew James Bottomley, Gaetano Barbato, Tommaso Eliseo, Maurizio Paci, Frank Narjes, Raffaele De Francesco, Vincenzo Summa, Uwe Koch, Renzo Bazzo, Daniel O. Cicero
  • Journal of Molecular Biology, January 2009, Elsevier
  • DOI: 10.1016/j.jmb.2008.11.017

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http://dx.doi.org/10.1016/j.jmb.2008.11.017