What is it about?
We conduct a thorough review of the public health and epidemiological literature over the last decade to determine what is of significance for PFAS health effects on children.
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Why is it important?
We determine that through in utero, neonatal and childhood PFAS exposures, there is strong evidence for immunosuppression, with diminished childhood antibody response to vaccination, particularly with PFOA, PFOS and PFHxS exposures; there are some indication of increased risks of childhood infectious diseases/infections, particularly from PFOS exposures, there are limited indication of an effect of PFAS exposure on allergic reactions/allergen specific IgE antibodies and limited indication of an effect of PFAS exposure on atopic dermatitis (AD) and for an effect of PFAS exposure on asthma and lung function.
Perspectives
Our study indicates the significant findings for exposures from the 'forever chemicals' of PFAS upon children as determined by the research literature over the last decade. We specify the nature of effects from these exposures along with relative degree of confidence for each.
Zygmunt Dembek
Battelle Memorial Institute
Read the Original
This page is a summary of: Perfluoroalkyl substances exposure and immunity, allergic response, infection, and asthma in children: review of epidemiologic studies, Heliyon, October 2021, Elsevier,
DOI: 10.1016/j.heliyon.2021.e08160.
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