What is it about?
Influenza A H1N1 viruses cause seasonal outbreaks every year but there are no effective antivirals against them, we develop compounds with double targets as possible antivirals.
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Why is it important?
The search for effective antivirals against several subtypes of influenza A
Perspectives
It is of great interest to have compounds available even for strains resistant to antivirals.
J Leopoldo Aguilar-Faisal
Instituto Politecnico Nacional
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This page is a summary of: Design, in silico studies, synthesis and in vitro evaluation of oseltamivir derivatives as inhibitors of neuraminidase from influenza A virus H1N1, European Journal of Medicinal Chemistry, March 2017, Elsevier,
DOI: 10.1016/j.ejmech.2017.01.039.
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