What is it about?
• [18F]FDG PET/CT is a quantitative imaging technique that requires strict standardisation to ensure repeatability and reproducibility. • Harmonised acquisition, reconstruction and quantification protocols are essential for reliable SUV-based assessments, especially in multicentre settings. • Updated recommendations reflect recent technological advances, including digital and long axial field-of-view PET/CT systems. • EARL standards (version 2) are recommended to ensure comparable quantitative performance across scanners. • Standardised procedures enhance the clinical value of PET/CT for staging, response assessment, prognosis and treatment decision-making.
Featured Image
Photo by martin lea on Unsplash
Why is it important?
Inconsistent PET/CT protocols and quantification methods can lead to variability in SUV measurements, potentially affecting clinical decisions and trial outcomes. These guidelines provide a unified framework that improves data comparability across institutions, supports evidence-based use of [18F]FDG PET/CT, and strengthens its role as an imaging biomarker in oncology and clinical research.
Perspectives
• It represents a comprehensive update of previous EANM guidelines, integrating new evidence and technological developments. • It places strong emphasis on quantitative harmonisation and reproducibility, aligning clinical practice with modern multicentre trial requirements. • It provides practical, consensus-based recommendations that are directly applicable in routine clinical workflows and research settings.
Arturo Chiti
Universita Vita Salute San Raffaele
Read the Original
This page is a summary of: [18F]FDG PET/CT: EANM procedure guidelines for tumour imaging: version 3.0, The EANM Journal, December 2025, Elsevier,
DOI: 10.1016/j.eanmj.2025.100006.
You can read the full text:
Contributors
The following have contributed to this page
