What is it about?

This research shows that ginger has an important chemo-preventative impact on liver cancer by inhibiting the growth of cells and inducing apoptosis. By reducing oxidative and inflammatory damage, ginger protects rat liver against cancer.

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Why is it important?

Based on our findings, we suggest that ginger herbal extract promotes a strong protective effect against DEN-mediated liver carcinogenesis.

Perspectives

Ginger and its nutraceutical active ingredients could protect rat liver from cancer via synergistic multi targeted effects including antioxidants and anti-inflammatory via down regulation of NF-kB. More work of standardized extracts of ginger that involves clinical trials and pharmacokinetic studies are recommended in the future.

Dr Alaaeldin A Hamza
National Organization for Drug Control and Research

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This page is a summary of: Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/ inflammation pathway, Biomedicine & Pharmacotherapy, February 2021, Elsevier, DOI: 10.1016/j.biopha.2020.111102.
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