What is it about?
We studied the places of contact between the various machines that transform biological energy. These paired locations, mapped precisely to the parts that contact each other, provide a glimpse of the topology of these machines while they're in action, and how they could coordinate with each other.
Photo by Bill Oxford on Unsplash
Why is it important?
Nobody knows how these molecular machines talk to one another to synchronize their work - even though transforming energy is the most essential task for molecules to come to life.
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This page is a summary of: The mitochondrial interactome visualized by crosslinking mass spectrometry, Biochimica et Biophysica Acta (BBA) - Bioenergetics, August 2016, Elsevier, DOI: 10.1016/j.bbabio.2016.04.045.
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