What is it about?

Preeclampsia is a severe pregnancy condition, and we're trying to find better ways to predict it early. We used blood samples and examined particular substances (metabolites) in pregnant women to see if they could help predict preeclampsia. We did this study with pregnant women of different body sizes. What we found: Some metabolites and amino acid ratios in the blood were linked to a higher risk of preeclampsia. The link between these markers and preeclampsia differed depending on a woman's body mass index (BMI). This suggests that different factors may contribute to preeclampsia in women with different body sizes.

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Why is it important?

This research is unique because it shows that we can use markers in the blood to predict preeclampsia and consider the influence of a woman's body size. It's timely because preeclampsia is a significant concern for pregnant women, and better prediction methods can help doctors provide better care and reduce complications during pregnancy.


I'm excited about this study because it brings us closer to understanding and preventing preeclampsia, which can be a severe condition for pregnant women. It's fascinating to see how different factors come into play based on a woman's body size. This research could lead to more personalized and effective prenatal care, which is excellent news for moms and babies.

Dr Ana Paula Panigassi
Metabolomic Diagnostics Ltd

Read the Original

This page is a summary of: First-trimester preterm preeclampsia prediction with metabolite biomarkers: differential prediction according to maternal body mass index, American Journal of Obstetrics and Gynecology, December 2022, Elsevier,
DOI: 10.1016/j.ajog.2022.12.012.
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