A recommended workflow for DNase I footprinting using a capillary electrophoresis genetic analyzer

Smitha Sivapragasam, Anuja Pande, Anne Grove
  • Analytical Biochemistry, July 2015, Elsevier
  • DOI: 10.1016/j.ab.2015.04.013

How to do DNaseI footprinting

What is it about?

DNaseI foot printing may be done using fragment analysis on a DNA sequencer. This methods update provides an optimized workflow that avoids technical problems and pitfalls inherent to the technique.

Why is it important?

If not performed accurately, incomplete or even misleading information may be obtained, compromising interpretation.

The following have contributed to this page: Prof. Anne Grove