Natural compounds with antidiabetic effects

What is it about?

Diabetes is a metabolic disorder in which a lack of insulin production or disturbances in the utilization of insulin lead to high concentrations of glucose in the blood and urine. In recent years, diabetes has reached almost epidemic proportions, possibly because of the changes in human lifestyle, which include dietary habits and a more sedentary form of living. Scientists are taking a closer look at both plants and animals, including marine entities, as sources of compounds for more efficacious and safer antidiabetic drugs at a cheaper cost.

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Why is it important?

A number of promising leads have emerged and are covered in this chapter. The chapter also discusses two important factors that are now recognized in the pathophysiology of diabetes and diabetes-induced loss of vision, kidney function, and dementia, namely oxidative stress and gut dysbiosis. It is possible that a fresh approach towards diabetes in the breaking of the diabetes-oxidative stress/dysbiosis-diabetes cycle with the aid of better glucose-lowering drugs, antioxidants, and probiotic symbionts may enable us to finally conquer this dread disease.