Advances in FEM Analysis for Cancer Therapy Focusing on Magnetic Nanoparticle Hyperthermia

What is it about?

This mini review provides a thorough examination of recent advances in finite element analysis (FEA) for cancer therapy, with a focus on magnetic nanoparticle (MNP) hyperthermia. The paper begins by discussing the fundamental principles of FEA and their applications in biomedical sciences. It then describes the application of FEA to the in vitro and in vivo modeling of MNP hyperthermia, including the development and validation of computational models that simulate magnetic nanoparticles behavior under alternating magnetic field (AMF), heat generation, its transfer, and cellular/tissue responses. The review further explores the emerging trends and future directions in the application of FEA for MNP hyperthermia, including the integration of experimental data, incorporation of patient-specific parameters, and optimization of treatment protocols. The paper also discusses the key challenges and limitations of current FEA models, shedding light on potential areas for future research and development. By synthesizing the most recent advances in this field, the review aims to provide a valuable resource for researchers, clinicians, and engineers working on the optimization and clinical translation of MNP hyperthermia for effective cancer therapy.

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Keywords: Finite element modeling, MNP hyperthermia, Cancer therapy, Biomedical engineering

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