The protective effect of α-hederin, the active constituent of Nigella sativa, on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs

What is it about?

Many investigations have demonstrated the prophylactic effect of Nigella sativa on asthma disease. One of its active constituents is a-hederin. In the present study, the preventive effect of two different concentrations of a-hederin on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs was examined.

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Why is it important?

This study suggested that a-hederin has anti-inflammatory and bronchodilatory effects like thymoquinone.