What is it about?
The present study is aimed at evaluating the clinical significance of plasma concentration of MMP-9 in chronic pancreatitis.
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Why is it important?
Pancreatic fibrosis is a key pathological feature in the etiology of chronic pancreatitis that leads to obliteration of exocrine and endocrine pancreatic tissues and its replacement by fibrous tissue resulting in clinical manifestations. Matrix metalloproteinase 9 is a member of the MMP family that is also known as gelatinase B, degrades type IV collagen of extracellular matrix and basal membrane.
Perspectives
The present study revealed a significant increase of plasma MMP 9 levels in chronic pancreatitis patients compared to control subjects.
Dr Sri Manjari K
BRIC Centre for DNA Fingerprinting and Diagnostics
Read the Original
This page is a summary of: Role of Plasma MMP 9 levels in the Pathogenesis of Chronic Pancreatitis, Indian Journal of Clinical Biochemistry, January 2011, Springer Science + Business Media,
DOI: 10.1007/s12291-010-0103-1.
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