What is it about?
We report a case who was treated with hydroxyurea 500 mg/day. The patient has developed palmoplantar hyperpigmentation after receiving 22 months of hydroxyurea therapy.
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Why is it important?
Hydroxyurea is a well-tolerated drug but can cause mucocutaneous side effects including hyperpigmentation of the skin, nails, and mucous membrane; and ulcer of the legs.
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This page is a summary of: Acral Hyperpigmentation Resulting from Hydroxyurea Therapy in Primary Myelofibrosis, Indian Journal of Hematology and Blood Transfusion, March 2018, Springer Science + Business Media,
DOI: 10.1007/s12288-018-0940-2.
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