What is it about?
the different factors that affect the outcome of living donor liver transplantation for patients with hepatocellular carcinoma (HCC)
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Why is it important?
Liver transplantation (LT) is in theory the optimal treatment for cirrhotic patients with HCC, due to the advantage of removing the tumor, and preventing the possibility of metachronous lesions on underlying cirrhosis and restoring normal liver function. However, high recurrence rates and poor outcomes were recorded from the first era of LT. These poor results were mostly related to unrestrictive selection criteria, inclusion of patients with macroscopic vascular invasion, and lymph node involvement. The aim of this work was to study the different preoperative, operative, and postoperative factors that may affect the survival and recurrence of the tumor in HCC patients after LDLT
Perspectives
Expansion of selection criteria beyond Milan and UCSF had no increased risk effect on recurrence of HCC. Microvascular invasion was an independent risk factor for tumor recurrence.
Dr Hazem Mohamed Zakaria
National Liver Institute
Read the Original
This page is a summary of: Predictors of Outcome of Living Donor Liver Transplantation for Hepatocellular Carcinoma, Indian Journal of Surgery, April 2016, Springer Science + Business Media,
DOI: 10.1007/s12262-016-1474-1.
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