What is it about?
In this review, we discussed the roles of the CNS, gut, liver, microbiota, and muscle in energy regulation. This area serves as a study strategy and solution for addressing the rising global energy-related disorders, and more patient-tolerated, personalized medication will emerge.
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Why is it important?
Since energy disorder-related complications can burden society and impact individuals' long-term health, understanding the actual neural pathways for energy regulation could lead to more effective medications or strategies to enhance each person's well-being and healthcare. It could also assist patients who have difficulty maintaining caloric homeostasis.
Perspectives
Neuroendocrine control of energy may be an underrated area in energy homeostasis and the pathophysiology of metabolic disorders. Understanding this intersting and intricate process of neural-hormone activity and its associated evolutionary mechanism will help identify an optimized strategy to address energy and metabolic dysregulation.
Dr. Song Wen
Shanghai Pudong Hospital, Fudan University
Read the Original
This page is a summary of: An overview of energy and metabolic regulation, Science in China Series C Life Sciences, October 2018, Springer Science + Business Media,
DOI: 10.1007/s11427-018-9371-4.
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