Mouse Liver Microsomes models
What is it about?
Mouse liver microsome datasets were curated from the literature and used to build machine learning models. Leave out validation and cross testing was performed.
Why is it important?
Pruning out the moderately unstable / moderately stable compounds from the training set produced models with superior predictive power. Bayesian models displayed the best predictive power for identifying compounds with a half-life ≥1 hour.
The following have contributed to this page: Dr Sean Ekins