What is it about?
We have described here an activity assay for Dopamine-β-hydroxylase Activity which employs for the first time Ultra high performance liquid chromatography and the common place absorbance based Photo Diode Array(PDA) detector.
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Why is it important?
This method is simple, less time consuming, economical and doesn't involve column switching or derivatization procedures.
Perspectives
This method may help in it's wide spread use in pharmacogenetics and in screening inhibitors for Dopamine-β-hydroxylase .
Dr. Toyanji Joseph Punchaichira
University of Delhi
Read the Original
This page is a summary of: Determination of Dopamine-β-hydroxylase Activity in Human Serum Using UHPLC-PDA Detection, Neurochemical Research, October 2018, Springer Science + Business Media,
DOI: 10.1007/s11064-018-2653-1.
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