What is it about?
Flucytosine-β-cyclodextrin and hydroxypropyl β-cyclodextrin water soluble inclusion complex were prepared by freeze drying method in distilled water. The formation of inclusion complex has been studied and fully described in our previous work
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Why is it important?
As expected the new inclusion complexes presents a semnificative increase of the antifungal activity, illustrated by the reduction of the minimal inhibitory concentrations for 50 and 90% of the tested strains decreased.
Perspectives
These results recommend the described conjugates as future promising therapeutic agents.
Prof. Liviu Dan MIRON
Universitatea de Stiintele Vietii "Ion Ionescu de la Brad" din Iasi
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This page is a summary of: Water soluble 5 FC complexes, preliminary pharmacological studies, Journal of Inclusion Phenomena and Macrocyclic Chemistry, May 2009, Springer Science + Business Media,
DOI: 10.1007/s10847-009-9594-x.
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