What is it about?
Genomic imprinting (GI) is a unique phenomenon that occurs in placental mammals, marsupials, and a subset of flowering plants. Genomic imprinting plays a key role in maintaining normal embryogenesis, and prenatal and postnatal growth.
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Why is it important?
DNA methylation and histone modifications play a key role in the process of imprinting. This review focuses on the role of DNA methylation in imprinting process and describes DNA methylation aberrations in different imprinting disorders.
Perspectives
Genomic imprinting is an epigenetic phenomenon that is involved in normal growth, viability, and embryonic development.
Dr Amr R Elhamamsy
Tanta University
Read the Original
This page is a summary of: Role of DNA methylation in imprinting disorders: an updated review, Journal of Assisted Reproduction and Genetics, March 2017, Springer Science + Business Media,
DOI: 10.1007/s10815-017-0895-5.
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