What is it about?
Sperm Dna is circular compared to helical DNA in a somatic cell . The helical to circular DNA change involves nuclear condensation with the histones replaced by protamine .chromomycin A3 staining pickup defect in this process .
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Why is it important?
DNA fragmentation is caused by many sites and protamination is one site and chromomycin A3 string is good tool
Perspectives
Following the publication ,this article has 18 citation and published in 2012 Anticipate greater utility in future compared to the current method of tests
Dr RAMARAJU G A
Krishna IVF Clinic
Read the Original
This page is a summary of: CASA derived human sperm abnormalities: correlation with chromatin packing and DNA fragmentation, Journal of Assisted Reproduction and Genetics, November 2012, Springer Science + Business Media,
DOI: 10.1007/s10815-012-9885-9.
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