What is it about?
A diagnosis of bacterial infections was obtained in 0% patients with CSF PTX3 levels < 3.6 ng/mL vs 58% of those with CSF PTX3 levels ≥ 3.6 ng/mL (p = 0.017). CSF PTX3 levels are higher in bacterial meningitis than aseptic meningoencephalitis. A cutoff of 3.6 ng/mL of CSF PTX3 has a high NPVand can be used to exclude bacterial CNS infections
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Why is it important?
Fist paper identifying CSF pentraxin cutoffs to distinguish between viral and bacterial CNS infections
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This page is a summary of: Determination of pentraxin 3 levels in cerebrospinal fluid during central nervous system infections, European Journal of Clinical Microbiology & Infectious Diseases, December 2019, Springer Science + Business Media,
DOI: 10.1007/s10096-019-03767-w.
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