What is it about?
The paper is devoted to new method of time-domain fluorescence molecular lifetime tomography (FMLT) based on asymptotic approximation to the fluorescence source function. Such an approximation helps to simplify the expressions that describe the FMLT reconstruction model in the time domain and to formulate the linear inverse problem for image reconstruction.
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Why is it important?
The paper analyses the results the authors have obtained during last 5 years in their testing the method in numerical and physical experiments. The analysis made it possible to identify shortcomings in the experiments and formulate directions for further research.
Perspectives
Experiments will be performed on phantoms and in the future on animals in order to verify the method as a sub-millimetre resolution method.
Dr. Alexander B Konovalov
Federal State Unitary Enterprise “Russian Federal Nuclear Center – Zababakhin All-Russia Research Institute of Technical Physics,” Snezhinsk, Russia
Read the Original
This page is a summary of: Fluorescence molecular lifetime tomography based on asymptotic source function approximation: prospects for solving the problem, Applied Physics B Photophysics and Laser Chemistry, August 2025, Springer Science + Business Media,
DOI: 10.1007/s00340-025-08539-3.
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