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Many hydrocarbons, especially polyaromatic hydrocarbons are insoluble in aqeous solutions. In this study, hydrophilic polymers were supplemented to increase solubility of hydrophobic isoflavones in aqueous whole-cell reaction system. Polyvinylpyrrolidone was verified to enhance solubility of daidzein mostly, which derived more than 1 g/L production of (S)-equol from daidzein in a simple whole-cell catalysis. The hydrophliic polymer could be used to enhance aqeuous solubility of a variety of plant polyphenols.
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This page is a summary of: Polymeric solvent engineering for gram/liter scale production of a water-insoluble isoflavone derivative, (S)-equol, Applied Microbiology and Biotechnology, June 2018, Springer Science + Business Media,
DOI: 10.1007/s00253-018-9137-8.
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