Decreased cryoprecipitate use and blood loss with the use of human fibrinogen concentrate.

What is it about?

This manuscript demonstrates in a prospective randomized trial that using human fibrinogen concentrate in pediatric cardiac surgery results in less blood loss and less use of cryoprecipitate

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Why is it important?

Human fibrinogen concentrate is derived from human plasma and undergoes a proprietary process that removes almost all infectious agents. This means we can use it instead of cryoprecipitate, which is derived from multiple blood donors. Thus, we can achieve hemostasis (blood clotting) due to decreased fibrinogen with this agent and drastically reduce the probability of blood borne pathogens, like HIV or hepatitis.

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