What is it about?
With a saturated genetic map, the confidence interval for location of a segregating QTL becomes a function of the experimental design, the QTL effect, and number of individuals genotyped. We present simple formula to calculate the confidence intervals for most important experimental designs
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Why is it important?
Contrary to accepted opinion at the time, increasing marker density helps only up to a point. Once marker "staturation" has been achieved, the limited factors for determination of confidence interal is the number of recombination events in the sample and the effect of the segregating effect.
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This page is a summary of: An analytical formula to estimate confidence interval of QTL location with a saturated genetic map as a function of experimental design, Theoretical and Applied Genetics, September 2004, Springer Science + Business Media,
DOI: 10.1007/s00122-004-1664-2.
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