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1-Benzyl-2-aminoadamantanes 2a–c, conformationally constrained aminoadamantanes 3a, b and 4 and diaminoadamantanes derivatives 5a–c, 6a–c were synthesized and tested as antiproliferative agents. The in vitro biological evaluation showed a significant difference in activity between 1-phenyl and 1-benzyl derivatives.
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This page is a summary of: New aminoadamantane derivatives with antiproliferative activity, Medicinal Chemistry Research, September 2013, Springer Science + Business Media,
DOI: 10.1007/s00044-013-0798-7.
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