What is it about?
When the spinal cord was cut, the inhibitory effect of a 5-HT2 antagonist on morphine analgesia was eliminated
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Why is it important?
Before this, it was not clear whether the serotonin type-2 receptors (5-HT2) were in the brain or spinal cord. These results point towards the brain.
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This page is a summary of: Pirenperone does not attenuate morphine analgesia in spinal rats, Psychopharmacology, March 1990, Springer Science + Business Media,
DOI: 10.1007/bf02245797.
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