What is it about?
A simple deconvolution-based method to estimate drug absorption rate from the blood drug level data.
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Why is it important?
In the method, blood drug level after iv bolus administration is represented by a bi-exponential equation: A x exp(-alpha x t) + B x exp(-beta x t). Input parameters: A, B, alpha, beta After giving the actual blood drug levels at time intervals after oral administration, successfully, then the absorption rates can be generated.
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This page is a summary of: Estimation of drug absorption rates using a deconvolution method with nonequal sampling times, Journal of Pharmacokinetics and Biopharmaceutics, April 1986, Springer Science + Business Media,
DOI: 10.1007/bf01065261.
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