What is it about?

The study evaluates the effectiveness and safety of aliskiren, either alone or combined with hydrochlorothiazide (aliskiren HCT), for treating hypertension in a real-world setting. Aliskiren has shown promise in clinical trials, but this study aims to assess how well it works and how safe it is for a diverse population in their daily lives. [Some of the content on this page has been created by AI]

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Why is it important?

Hypertension is a common condition that can lead to serious health problems like heart disease and stroke if not properly managed. Medications like aliskiren offer a way to control blood pressure and reduce the risk of complications. By studying its effectiveness and safety in a real-world setting, healthcare providers can better understand how well aliskiren works for different people and ensure they receive the best treatment possible. Key Takeaways: 1. Aliskiren, either alone or in combination with hydrochlorothiazide, effectively lowers blood pressure in patients with hypertension, with over 70% of patients achieving the target blood pressure level. 2. Both aliskiren and aliskiren HCT lead to significant reductions in blood pressure from baseline, demonstrating their effectiveness in controlling hypertension. 3. More than 80% of patients experienced a positive response to treatment, indicating that aliskiren-based therapy is generally effective for a wide range of individuals. 4. Aliskiren treatment was well-tolerated, with a small proportion of patients experiencing adverse events, suggesting it is a safe option for hypertension management. 5. These findings support the use of aliskiren-based regimens as an effective and safe treatment option for hypertension in diverse populations, contributing to better management of this common health condition.

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This page is a summary of: Effectiveness and Safety of Aliskiren and Aliskiren Hydrochlorothiazide (HCT) in a Multiethnic, Real-World Setting, Advances in Therapy, January 2013, Springer Science + Business Media,
DOI: 10.1007/s12325-013-0005-8.
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