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β-Adrenergic receptors (βARs) belong to a large family of cell surface receptors known as G protein-coupled receptors (GPCRs). They are coupled to Gs protein (Gαs) for the activation of adenylyl cyclase (AC) yielding cyclic AMP (AMP), and this provides valuable responses, which can affect the cardiac function such as injury. The binding of an agonist to βAR enhances conformation changes that lead to the Gαs subtype of heterotrimeric G protein which is the AC stimulatory G protein for activation of AMP in the cells.

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This page is a summary of: β-Adrenergic receptor, an essential target in cardiovascular diseases, Heart Failure Reviews, August 2019, Springer Science + Business Media,
DOI: 10.1007/s10741-019-09825-x.
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