Analysis of Pemphigus Vulgaris

What is it about?

There are two main different variants of pemphigus vulgaris: one is the mucocutaneous variant and the other is the mucosal dominant variant. The mucosal dominant variant of pemphigus vulgaris involves autoantibodies against only desmoglein 3, whereas the mucocutaneous variant involves autoantibodies against both desmoglein 1 and 3. Some patients, however, report never having musocal lesions and are classified as having cutaneous-only disease.

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