What is it about?

This paper provides an overview of the methods available in the literature to model endovascular therapies for cerebral aneurysms. Endovascular therapies like coiling and stening aim at closing cerebral aneurysms by promoting blood clots and are delivered endovascularly and in a minimally invasive fashion. This makes them more attractive than surgical alternatives that require craniotomy. What this paper describes is how to model these procedures in computers so that interventions can be plan personally and optimally.

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Why is it important?

There is evidence that the same medical device can have different outcome on different types of patients and that different devices perform differently on a single individually. This leads to the need to personalise treatment and, with this, the need to be able to plan the optimal strategy for an individual. Computational modelling is central to realise this goal.

Perspectives

This is the most comprehensive review on this topic to date and the first in emphasising the need to think in terms of uncertainty in both models and parameters in the context of interventional planning.

Prof Alejandro F Frangi
University of Leeds

Read the Original

This page is a summary of: Virtual endovascular treatment of intracranial aneurysms: models and uncertainty, WIREs Systems Biology and Medicine, May 2017, Wiley,
DOI: 10.1002/wsbm.1385.
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