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Patients that develop pre-eclampsia or fatal growth restriction show signs of impaired placental function. This can possibly reduce the amount of fetal DNA in cell-free DNA testing for Down's syndrome. We show an association of fetal fraction on this test with other markers for pre-eclampsia in the first trimester of the pregnancy.

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This page is a summary of: Association between fetal fraction on cell‐free DNA testing and first‐trimester markers for pre‐eclampsia, Ultrasound in Obstetrics and Gynecology, October 2018, Wiley,
DOI: 10.1002/uog.18993.
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