What is it about?
A consortium of 13 laboratories across 11 universities in 7 countries to agree on nomenclature for various cell types called endothelial progenitors.
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Why is it important?
Various different cell types have been all named EPCs. Therefore, EPC terminology is too vague as it acts as an umbrella term for distinct cell subtypes. Here, leaders on the EPC field encourage scientist to standardise a more accurate terminology for cells isolated in culture by using their lineage such as endothelial colony forming cells (ECFCs) and myeloid angiogenic cells (MACs).
Perspectives
Standardization of nomenclature is critical for experimental reproducibility. Endothelial progenitor cell biology has suffered from the use of vague terminology. This paper highlights the need for scientists to use same accurate terminology.
Dr Reinhold J Medina
Queen's University Belfast
Read the Original
This page is a summary of: Endothelial Progenitors: A Consensus Statement on Nomenclature, Stem Cells Translational Medicine, March 2017, Wiley,
DOI: 10.1002/sctm.16-0360.
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