What is it about?
Kaempferol, a kind of flavonoid compounds, has been identified as a potential cancer therapeutic agent. However, the changes in the topography of cell membrane induced by kaempferol at subcellular- or nanometer-level were still unclear. In this work, the topographical changes of cytomembrane in human cervical cancer cell (SiHa) induced by kaempferol, as well as the role of kaempferol in apoptosis induction and its possible mechanisms, were shown.
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Why is it important?
These results showed structural characterizations of cellular topography in kaempferol-induced SiHa cell apoptosis and might provide novel integrated information from macro to nano level to assess the impact of kaempferol on cancer cells, which was important for the understanding of the anti-cancer mechanisms of drugs.
Perspectives
Kaempferol is well worth investigating further.
Professor Sui-Ping Deng
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Read the Original
This page is a summary of: The mechanism of kaempferol induced apoptosis and inhibited proliferation in human cervical cancer SiHa cell: From macro to nano, Scanning, February 2016, Wiley,
DOI: 10.1002/sca.21312.
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