What is it about?
This is the first study in which the pharmacokinetics and integrated dose measure of a mixture of bioactive chemicals in an herbal product is predicted by a model.
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Why is it important?
The integrated dose measure of bioactive chemicals helps to assess dose-response relation and safety assessment of an herbal product. The modeling approach described in this study is also applicable to the bioactive chemicals of other plant-based drugs, foods and nutraceuticals.
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This page is a summary of: Physiologically based pharmacokinetic modeling of tea catechin mixture in rats and humans, Pharmacology Research & Perspectives, April 2017, Wiley,
DOI: 10.1002/prp2.305.
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