What is it about?
The aim of this study was to perform a review of the literature on the important role of fluoxetine in anti-inflammatory, cell survival, and neuron trophicity mechanisms (antiapoptotic properties) as well as its role regarding enzymes of the antioxidant defense system.
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Why is it important?
This study reports the important anti-inflammatory, antiapoptotic, and antioxidant functions of fluoxetine and suggests that the clinical benefits of its administration are related to the cell-modulating functions in the central and peripheral nervous systems.
Perspectives
I was very pleased to write this article because I could see several important functions of Fluxoxetine in relation to inflammatory processes, cellular apoptosis and antioxidant activity. I believe that many other studies need to be performed to assess all the beneficial functions as well as the harmonics of using fluoxetine.
Vitor Caiaffo
Universidade Federal de Pernambuco
Read the Original
This page is a summary of: Anti‐inflammatory, antiapoptotic, and antioxidant activity of fluoxetine, Pharmacology Research & Perspectives, April 2016, Wiley,
DOI: 10.1002/prp2.231.
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