What is it about?
In this manuscript we have curated a database of protein-RNA complexes and their unbound structures from the Protein Data Bank. This would provide a benchmark to analyze how the binding partners undergoes structural changes upon binding with each other
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Why is it important?
This benchmark is important to understand how the conformational flexibility govern the protein-RNA association. Moreover, it is useful to benchmark the docking algorithms.
Perspectives
This article would be a great resources to the computational biologists/Bioinformaticians, who try to develop protein-RNA docking algorithm. We will keep updating the benchmark and a second version is also currently available which is published in proteins, 2017;85:256-267.
Ranjit Bahadur
Read the Original
This page is a summary of: A protein–RNA docking benchmark (I): Nonredundant cases, Proteins Structure Function and Bioinformatics, May 2012, Wiley,
DOI: 10.1002/prot.24083.
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