What is it about?
We summarize the sequence features that characterize MarR family transcription factors that bind urate. We also identify bacterial species in which these proteins are encoded.
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Why is it important?
Urate is produced by host cells when they defend themselves against an infection. Urate-responsive transcription factors can use this diffusible signal to control virulence gene expression.
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This page is a summary of: MarR homologs with urate-binding signature, Protein Science, February 2011, Wiley,
DOI: 10.1002/pro.588.
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