A researcher's guide to mass spectrometry-based proteomics

What is it about?

In this tutorial, we visually describe what happens to ions as they enter and move around inside a mass spectrometer. In layman's terms, we describe basic MS principles, including electric current, ion optics, ion traps, quadrupole mass filters, and Orbitrap FT-analyzers.

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Why is it important?

This article is meant to help make mass spectrometry-based proteomics less of a "black box" for users in biomedical research.