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Given the lack of adverse events associated with IV alteplase in our patient, we advocate cautious evaluation for potential reversal of acutely administered anticoagulation to facilitate alteplase administration in severely disabled patients who are not eligible for mechanical intervention and would have been excluded from definitive AIS treatment.
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This page is a summary of: Alteplase for Acute Ischemic Stroke after Heparin Reversal with Protamine: A Case Report and Review, Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy, September 2017, Wiley,
DOI: 10.1002/phar.1997.
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