What is it about?
Using a dye technique to show areas of metaplasia in the larynx without the need for microscopy.
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Why is it important?
Previously, the only way to detect cellular metaplasia in the larynx was by painstaking histological methods involving the preparation of multiple strips of laryngeal tissue, processing the tissue and preparing microscope slides for examination.
Perspectives
It was a privilege to work with Doctors James Watt and Philip Stell to experiment and discover ways to immediately demonstrate changes in the lining cells of the human larynx after surgical removal or at autopsy. Being able to demonstrate changes macroscopically, greatly facilitated identifying areas of interest (metaplasia) and specific locations at which tissue could be removed for microscopic examination.
Irene Gregory Wilkinson
Institute of Biomedical Sciences
Read the Original
This page is a summary of: A simple method for the post-mortem demonstration of squamous metaplasia in the larynx, The Journal of Pathology, June 1971, Wiley,
DOI: 10.1002/path.1711040210.
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