The Efficacy of Platelet-Rich Plasma Injection in the Management of Hip Osteoarthritis: A Systematic Review Protocol

Ivan Medina-Porqueres, Patricia Alvarez-Juarez
  • Musculoskeletal Care, July 2015, Wiley
  • DOI: 10.1002/msc.1115

Systematic Review Protocol on the effectiveness of PRP Injection for Hip Osteoarthritis

What is it about?

BACKGROUND: Hip Osteoarthritis (HOA) is a progressively debilitating condition that is associated with pain and morbidity. The main objectives of HOA management are to relieve pain, educate the patients about their disease, restore function, minimize the progression of the disease and maintain health-related quality of life. However, there is no known cure for HOA, so the main therapeutic strategy is symptomatic. This is the first review aimed to summarise available evidence on effectiveness of Platelet-Rich Plasma (PRP) in the management of HOA. METHODS AND ANALYSIS: Electronic databases will be searched using a strategy developed by the researchers using the Medical Subject. Headings (MeSH) pertaining to each database. A primary search to retrieve primary studies published will be performed through five electronic databases: Pubmed, ProQuest Health & Medical Complete, CINAHL, E-journals and SPORTdiscus). The study selection process will be a two-stage approach; title and abstract screen for inclusion, followed by a review of selected full-text articles by two independent reviewers. Data will be extracted using standardised piloted data extraction forms. Risk of bias will be critically appraised using standard checklists based on study designs. Summary tables will be created showing key study characteristics. Disagreements between the reviewers at any phase will be resolved by discussion and consensus. This protocol for systematic review is prepared according to the Preferred Reporting Items for Systematic review and Meta-analysis for Protocols-2009 statement. ETHICS AND DISSEMINATION: Ethical approval is not obtained as original data will not be collected as part of this review. PROSPERO REGISTRATION NUMBER: CRD 42014010210

Why is it important?

To the authorsĀ“ knowledge, no previous study has systematically reviewed and critiqued the efficacy of PRP in the treatment of HOA.


Professor Ivan Medina-Porqueres
University of Malaga

The completed review will be submitted for publication in any peer-reviewed journal.

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The following have contributed to this page: Professor Ivan Medina-Porqueres