What is it about?

CEST MRI May be used to measure changes of hydroxyl metabolites in kidney during progression of diabetic nephropathy.

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Why is it important?

Diabetic nephropathy (DN) is the leading cause of renal failure; however, current clinical tests are insufficient for assessing this disease. DN is associated with changes in renal metabolites, so we evaluated the utility of chemical exchange saturation transfer (CEST) imaging to detect changes characteristic of this disease.

Perspectives

Experimental design, data acquisition, data analysis, writing

Dr Feng Wang
Vanderbilt University

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This page is a summary of: Mapping murine diabetic kidney disease using chemical exchange saturation transfer MRI, Magnetic Resonance in Medicine, November 2015, Wiley,
DOI: 10.1002/mrm.26045.
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