Analysing bioassay data from the public domain for human P-glycoprotein inhibitors and substrates
What is it about?
We annotate in vitro assays used for the determination of bioactivities of human P-glycoprotein inhibitors and substrates in public databases and show that it is possible to combine data coming from the same assay type under certain conditions.
Why is it important?
For inhibitors of human P-glycoprotein it is possible to combine data coming from the same assay type, if the cell lines used are also identical. There is a need for larger chemical diverse datasets that have been measured in a panel of different assays as this would reduce the search for other inter-correlations between bioactivity data yielded by different assay setups.
The following have contributed to this page: Dr Antony John Williams
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