Putting an end to the Pseudomonas aeruginosa IQS controversy

Pierre Cornelis
  • MicrobiologyOpen, October 2019, Wiley
  • DOI: 10.1002/mbo3.962

IQS is not a quorum sensing molecule in Pseudomonas aeruginosa

What is it about?

IQS has been claimed to be a fourth cell-cell communication quorum sensing molecule in Pseudomonas aeruginosa and the proct of the ambABCDE genes. Several later publications show that it is not true. The object of this commentary is to demonstrate that IQS= aeruginaldehyde, a molecule derived from the pyochelin siderophore instead. Despite the evidence, the false information continues to circulate, even in recent review articles.

Why is it important?

The original publication about IQS is not correct but continues to be cited, hence the importance of this commentary.

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